Rhode Island College Biosafety Program


Your compliance is crucial to the success of the goals of the RIC Biosafety Program. Those working with recombinant DNA (rDNA) and/or biological materials are required to submit a Biological Project Registration Form to the Institutional Biosafety Committee. In some cases the form must go through review before laboratory work may begin. The following activities are exempt from full review, but still require the submission of a Biological Project Registration Form.

rDNA that does not present a significant risk to health or the environment

rDNA that is not in organisms or viruses

rDNA consisting entirely of DNA segments from a single non-chromosomal or viral DNA source

rDNA consisting entirely of DNA from a prokaryotic host including its indigenous plasmids or viruses when propagated only in that host or when transferred to another host by well established physiological means.

rDNA consisting entirely of DNA from a eukaryotic host including its chloroplasts, mitochondria, or plasmids when propagated only in that host.

rDNA consisting entirely of DNA segments from different species that exchange DNA by known physiological processes.

The rDNA activities listed above are exempt from full review before labwork is initiated; however, a Biological Project Registration Form must be filed with the IBC.

Activities involving Biological Materials, work with live organisms, and animals:

Biosafety Level 1 (BSL1) materials are not known to cause disease in healthy adults are exempt from full review. A Biological Project Registration Form must be filed with the IBC.

Fluids, tissues, cells and other biological material of human or non-human primate origin are classified as BSL2. Projects involving BSL2 materials are not exempt from full IBC review and are not authorized until the protocols are reviewed and approved by the IBC.

Use of the following Select Agents in research must go through IBC approval before obtaining materials.

Abrin, Conotoxins, Diacetoxyscirpenol (DAS), Ricin, Saxitoxin, Tetrodotoxin, Shiga-like ribosome inactivating proteins, Botulinum neurotoxins, Clostridium perfringens epsilon toxin, Shigatoxin, Staphylococcal enterotoxins, T-2 toxin


Investigator Resources:

Biological Project Registration Form

Biohazard symbols

Door placard

Inspection checklist





















Instructions for BPR Form:

Link to the RIC Biological Project Registration Form (fillable pdf)


This form can be filled out to register activities to be performed under a specific grant or contract (Specific project registration) or for activities performed regularly as part of multiple funded projects (Generic project registration).  See Section 1a.

Complete the appropriate sections as outlined below. If the research involves use of human or primate materials, you will need to have an “Exposure Control Plan” in place.  More details are provided in Section 8.

Required: Every Principal Investigator must complete the following and append the grant research description (if grant-funded) to this registration form:

  • Section 1 General Information
  • Section 2 Determination of exemption status
  • Section 10 Reporting of previous incidents
  • Section 11 Certification and Signatures

Additional General Information for non-exempt research:

  • Section 3 Laboratory Information
  • Section 4 Project Description

Research Specific Sections:  Complete the following sections if they are applicable to your research:

  • Section 5 for research involving recombinant DNA technologies.
  • Section 6 for research involving viable microorganisms or viruses.
  • Section 7 for research involving human and non-human primate materials including tissues and primate-derived cell lines. 
  • Section 8 for research requiring support from an occupational medical provider.
  • Section 9 for research involving the listed toxins.

When you have completed the form, email it to the RIC IBC Chair (ibcchair@ric.edu).  Print and sign Section 9, the Certification and Signature page and mail this to IBC Chair, RIC Biology Department.



  Last updated: September 17, 2013