Dr. William M. Holmes

Department, Office, or School
Department of Biology
  • Associate Professor

Education

Ph.D. Brown University

Selected Publications

Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding. Nature Communications 5 (2014): 4383

Defining the Limits: Protein Aggregation and Toxicity In Vivo. Critical Reviews in Biochemistry and Molecular Biology 49 (2014): 294-303.

Crystal Structure of inositol phosphate multikinase 2 and implications for substrate specificity. J. Biol. Chem. 281 (2006): 38109-38116.​​​

 

Courses

BIOL100
BIOL111
BIOL420

Research Interests

Protein Folding and Toxicity in Neurodegenerative Diseases